B.Pharmacy

To prepare and submit Hexamine from urea – Chemistry Practical

B.Pharmacy, Medicinal Chemistry

Aim: To prepare and submit Hexamine from urea. Requirements: Porcelain dish, formaldehyde, ammonium hydroxide solution, ethanol,  Theory: Hexamethylenetetramine or methanamine or urotropine is a heterocyclic organic compound with the formula (CH₂)6N4. This white crystalline compound is highly soluble in water and polar organic solvents. Reaction involved: Procedure: Add 7.0 g of 20% ammonium hydroxide solution […]

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Note on requirements for residual solvents in pharmaceutical products

B.Pharmacy, Pharmaceutical Quality Assurance

Write a Note on Requirements for residual solvents in pharmaceutical products. RESIDUAL SOLVENTS UNDER USP 467 (ICH Q3C) GUIDELINES Residual solvents in pharmaceuticals are defined by the ICH as organic volatile chemicals that are used or produced in the manufacture of drug substances, excipients, or in the preparation of drug products. In general, solvents are

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Short Note on Conduct of a non-clinical laboratory studies | Quality Assurance – B.Pharmacy 6th Semester

B.Pharmacy, Pharmaceutical Quality Assurance

Question: Write a short note on Conduct of a non-clinical laboratory studies. [Quality Assurance in Pharmacy] Answer: Read here: Protocol for non-clinical studies  Conduct of a non-clinical laboratory studies: The nonclinical laboratory study shall be conducted in accordance with the protocol. The test systems shall be monitored in conformity with the protocol. Specimens shall be identified

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Short Note on protocol for non-clinical studies | Quality Assurance B.Pharmacy 6th Semester

B.Pharmacy, Pharmaceutical Quality Assurance

Question: Write a short note on protocol for non-clinical studies. [Quality Assurance in Pharmacy] Answer: PROTOCOL FOR NON-CLINICAL STUDIES: Each study shall have an approved written protocol that clearly indicates the objectives and all methods for the conduct of the study. The protocol shall contain, as applicable, the following information: A descriptive title and statement

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To perform the assay of Metronidazole | Practical Medicinal Chemistry B.Pharm 6th Semester

B.Pharmacy, Medicinal Chemistry

Aim: To perform the assay of Metronidazole. IUPAC Name: 2-(2-methyl-5-nitro-1H-imidazol-1-yl) ethanolMolecular Formula: C6H9N3O3Mol. Wt.: 171.2.Metronidazole contains not less than 99.0 per cent and not more than 101.0 per cent of C6H9N30, calculated on dried basis.Category: Antiamoebic.Dose: For trichomoniasis, 200 mg thrice daily, for 7 days. For amoebiasis, 400 mg thrice daily, for 5 to 10

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To prepare/synthesize chlorobutanol from acetone

B.Pharmacy, Medicinal Chemistry

AIM: TO PREPARE AND SUBMIT CHLOROBUTANOL FROM ACETONE. Requirements: Acetone, chloroform, potassium hydroxide, round bottom flask, Glass rod and Beaker. Theory: Chloroform (trichloro-2-methyl-2-propanol) is synthesised by nucleophilic addition of chloroform and acetone. The reaction is base driven by sodium or potassium hydroxide. Procedure: Mix dry acetone (5g) and chloroform (10g) with continued stirring & cool

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To determine physicochemical and toxicity properties of Diazepam using free online services.

B.Pharmacy, Medicinal Chemistry

Aim: To determine physicochemical and toxicity properties using free online services. Theory:     Bringing a pharmaceutical drug to the market is a long term process that costs sixty-five thousand crores of Indian rupees. One promising approach for improving the efficiency and productivity of early discovery in the pharmaceutical industry and academia is Virtual screenings

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