Aim: To prepare and submit 7-hydroxy-4-methyl Coumarin from Resorcinol by green technique (Pechmann Condensation). REQUIREMENT: Ethyl acetoacetate, resorcinol, pipette, measuring cylinder. THEORY: Resorcinol reacts with ethyl acetoacetate in the presence of concentrated sulphuric acid to form 7-hydroxy-4-methyl Coumarin. PROCEDURE: Dissolve 1.1g resorcinol in 1.35g of ethyl acetoacetate in a 50ml dry round bottom flask. Add 1.5g K10-montmorilonite clay to the […]

AIM: TO SYNTHESISE PHENYTOIN FROM BENZIL AND UREA. REQUIREMENTS:  Chemicals: Benzil, Urea, Sodium hydroxide, Ethanol, Concentrated hydrochloric acid. Apparatus: Round bottom flask (100ml), Reflux condenser, Crystallizing dish (500ml), Heating mantle, Stirrer, Beaker (400ml), Filtering flask with Büchner funnel, Graduated cylinders (100ml and 50ml), Petri dish etc. BACKGROUND: Principle: Base catalysed reaction is used between benzyl

Aim: To prepare 6-Hydroxy nicotinic acid from Coumalic acid. Requirements: Sulphuric acid, coumalic acid, methanol, sodium carbonate, hydrochloric acid, sodium hydroxide. Theory: Methyl coumalate is formed from coumalic acid in the presence of methanol. 6-hydroxy nicotinic acid is formed by reaction between methyl coumalate and ammonia. Reaction Involved: Procedure: 1. Preparation of Methyl coumalate: Place

Aim: To prepare and submit Hexamine from urea. Requirements: Porcelain dish, formaldehyde, ammonium hydroxide solution, ethanol,  Theory: Hexamethylenetetramine or methanamine or urotropine is a heterocyclic organic compound with the formula (CH₂)6N4. This white crystalline compound is highly soluble in water and polar organic solvents. Reaction involved: Procedure: Add 7.0 g of 20% ammonium hydroxide solution