Physical Pharmacy

Important Question on Solubilization for BPharmacy 4th Semester Define Wetting. What are its applications? How surfactants are capable of wetting of powder. Define contact angle. Write its various values ranging from 0° to 180°. Define critical surface tension. Give its application. Define solubilization. Explain process of micelles solubilization with labelled diagram. 1. Define Wetting. What […]

Important Questions on Adsorption Isotherm: Define Adsorption isotherm. Describe in detail IUPAC classification of adsorbtion isotherm. When a substance moves away from a solution and adsorbs at the surface of a solid, the concentration of the solute remaining in solution is in dynamic equilibrium with the adsorbed concentration at the surface. This distribution ratio of

Important Questions: What are the assumption of Langmuir adsorption. Give its derivation. Write BET equation. Explain adsorption applications under following heading: A) Toxicity B) Purification C) Poisoning Solution And Explainations: 1. What are the assumption of Langmuir adsorption. Give its derivation. Assumptions in Langmuir Adsorption: The surface of solid posses fixed number of active sites

Important Questions: Define Adsorption. Difference between physical and chemical adsorption. Explain how solid surfaces offer a site for adsorption of gases & dissoluted solute through concept of surface tension. Give thermodynamic considerations for adsorption process. Define adsorption isotherm. Explain Freundlich isotherm with equation & plot. What are the factors which affect adsorption of solute molecules

Some Important Questions from Surface and Interfacial Phenomenon as per B Pharmacy PCI Pattern are: Who introduced the HLB concept and define HLB scale? Draw HLB scale with values of various surfactants along with examples. Enumerate various formulas for calculation HLB values. Explain RHLB (Required HLB). What are the various steps involved in detergency. Explain

Important Questions: Define surfactants. Define CMC (critical miscelleconcentration). Explain the mechanism of formation of micelles with diagram. Classify surfactants with suitable examples. Give medical applications of surfactants. Give pharmaceutical applications of surfactants. Explain how cationic amphiphiles posses antibacterial activity against gram negative organisms. Explain how amphiphiles above CMC decrease effectiveness of hexylresorcinol towards pinworms. Solutions:

Important Questions on Measurement of Surface & Interfacial Tension Physical Pharmacy Important Questions: Explain DuNouy Ring Method for determination of surface tension and interfacial tension. Give equation involved in this method. Explain Drop Weight and Drop Count Method for determination of surface tension. Explain Wilhelmy Plate Method for determination of Surface & Interfacial Tension. Explain

Physical Pharmacy Important Questions on Surface Free Energy & Measurement of Surface Tension – Interfacial phenomena Important Questions: Define Surface Free Energy. Derive an equation for determination of Surface Free Energy. ΔG = γΔA OR  W = γ x ΔA. Write applications of surface free energy equation in pharmacy? Deduce an equation to derive pressure difference across curved surface.